Page Last Updated: October 23, 2025
File-Based Dataπ
File-based data is provided for imaging, EEG, and biosensor recordings. Unlike tabulated data (tables organized in a uniform way across study instruments), file-based data comes in a variety of formats, often modality-specific. File-based data includes:
- Raw BIDS: raw data converted to the BIDS standard with unaltered signal content
- Derivatives: processed datasets generated by standardized pipelines
Raw BIDSπ
The rawdata/ folder includes raw file-based data in BIDS format for MRI, MRS, EEG, and wearable sensor recordings.
hbcd/
|__ rawdata/
|__ sub-{ID}/
| |__ sub-{ID}_sessions.tsv (+JSON)
| |__ ses-{V0X}/
| |__ anat/
| |__ dwi/
| |__ eeg/
| |__ fmap/
| |__ func/
| |__ motion/
| |__ mrs/
| |__ sub-{ID}_ses-{V0X}_scans.tsv (+JSON)
|
|__ dataset_description.json
|__ participants.tsv (+JSON)
Participant-, Session-, & Scan-Level Dataπ
Participant-, session-, and scan-level data are stored in the following .tsv files, accompanied by .json sidecar files containing metadata:
| Level | File Name | Description |
|---|---|---|
| Participant | participants.tsv |
Basic demographic and participant information (e.g., sex) |
| Session | sub-{ID}_sessions.tsv |
Session information (e.g., collection site, participantβs age at each session, head size) |
| Scan | sub-{ID}_ses-{V0X}_scans.tsv |
Per-scan information (age at scan and raw data QC scores - see HBCD MR Quality Control Procedures) |
Modality-Specific Subfoldersπ
Click the following links to see the full file contents of each raw BIDS folder in the measure documentation pages:
| Structural MRI | anat/ |
| Quantitative MRI | anat/ |
| Functional MRI | func/, fmap/ |
| Diffusion MRI | dwi/ |
| MR Spectroscopy | mrs/ |
| EEG | eeg/ |
| Wearable Sensors | motion/ |
BIDS Conversion Proceduresπ
Raw data for each modality are converted to the BIDS standard via the following software and procedures:
| BIDS Conversion | |
|---|---|
| MRI | DICOM images are converted using an HBCD-customized version of dcm2niix, with post-conversion modifications required for certain scan types to maintain consistency across vendors - see MRI Hardcoded Fields & Post-Conversion Modifications below for details. |
| MRS | Vendor-specific raw data formats (Siemens .dat; Philips data/list; GE P-file) were converted to BIDS using a wrapper (hbcd_mrs_to_nii_conversion) for spec2nii v0.7.0. |
| EEG | BIDS conversion was performed with the EEG2BIDS Wizard, a custom MATLAB application for HBCD EEG data management and formatting, installed at all HBCD sites. After each EEG session, raw data are uploaded to the Wizard, which converts them to the BIDS standard. |
| Sensors | See Jeung et al., 2024 Motion-BIDS: an extension to the brain imaging data structure to organize motion data for reproducible research |
Hardcoded Fields
Key fields for Philips (and GE for T1w scans) are hard-coded to ensure consistency across vendors, as NIfTI/JSON metadata can be omitted or misconfigured during conversion. Hardcoded fields for different modalities/scan types are outlined in the following table and also documented in the JSON sidecars under HardCodedValues. All of the following were modified for Philips only with the exception of T1w scans, modified for both Philips and GE.
| Modality | PhaseEncodingDirection |
TotalReadoutTime |
SliceTiming |
<Small|Large>Delta |
RepetitionTime |
|---|---|---|---|---|---|
| DWI | |||||
| EPI | |||||
| BOLD | |||||
| T1w (both Philips & GE) |
QALAS
QALAS conversion yielded either five 3D NIfTI files or one 4D file with five volumes and missing JSON headers. To standardize outputs, all series were split into five NIfTI files, each labeled by inversion time (inv-{X}). The JSON sidecars were updated as follows: T2Prep for QALAS file inv-0 is set to 0.10 for Siemens/Philips and 0.09 for GE. InversionTime (s) is hard-coded per manufacturer as follows:
| inv-0 | inv-1 | inv-2 | inv-3 | inv-4 | |
|---|---|---|---|---|---|
| Siemens | 0 | 0.1 | 1 | 1.9 | 2.8 |
| GE | 0 | 0.1193 | 1.0192 | 1.9191 | 2.8190 |
| Philips | 0 | 0.115 | 1.0105 | 1.9060 | 2.8016 |
MR Data Release Eligibility Criteriaπ
Acquisition parameters vary by scanner vendor, so inclusion criteria are typically defined as acceptable ranges rather than fixed values. Following BIDS conversion, modality-specific criteria are extracted from BIDS sidecar JSON files and evaluated accordingly.
NOTE: All images are additionally checked to confirm they were acquired using a head coil.
| Scan Type | Repetition Time (TR) | Echo Time (TE) | Inversion Time (TI) | Slice Thickness | Number of Volumes |
|---|---|---|---|---|---|
| T1w | 2.3 - 2.41 | 0.002 - 0.0035 | 1.06 - 1.1 | 0.8 | NA |
| T2w | 2.5 - 4.5 | 0.09 - 0.15 | 0.29 - 0.33 | 0.563 - 0.565 | NA |
| MRS Localizer | 2.5 - 4.5 | 0.09 - 0.15 | 0.29 - 0.33 | 0.563 - 0.565 | NA |
| Diffusion | 4.8 | 0.0880 - 0.0980 | NA | 1.7 | β₯ 90 (AP + PA) |
| EPI Fieldmap | 8.4 - 9.2 | 0.064 - 0.0661 | 2 | 0.563 - 0.565 | NA |
| Functional | 1.725 | 0.0369 - 0.0371 | NA | 2 | β₯ 87 (~2.5 min) |
Derivativesπ
The derivatives/ folder contains derivatives, which are file outputs from processing pipelines.
hbcd/
|__ derivatives/
# Structural & Functional MRI
|__ mriqc/
|__ bibsnet/
|__ nibabies/
|__ freesurfer/
|__ mcribs/
|__ xcp_d/
|
# Quantitative MRI
|__ symri/
|__ qmri_postproc/
|
# Diffusion MRI
|__ qsiprep/
|__ qsirecon/
|__ qsirecon-DIPYDKI/
|__ qsirecon-DSIStudio/
|__ qsirecon-TORTOISE_model-MAPMRI/
|__ qsirecon-TORTOISE_model-tensor/
|
|__ osprey/ # MRS
|__ made/ # EEG
|__ hbcd_motion/ # Biosensor Recordings
Links to Pipeline Derivativesπ
| Modalities | Derivatives Folder | Pipeline Name & Link to Derivatives Link |
|---|---|---|
| Structural & Functional MRI | mriqc/ |
MRIQC - sMRI & fMRI |
bibsnet/ |
BIBSNet | |
nibabies/ |
Infant fMRIPrep (or Nibabies) | |
freesurfer/ & mcribs/ |
FreeSurfer & M-CRIB-S | |
xcp_d/ |
XCP-D | |
| Quantitative MRI | symri/ |
SyMRI |
qmri_postproc/ |
qMRI PostProc | |
| Diffusion MRI | qsiprep/ |
QSIPrep |
qsirecon/ |
QSIRecon | |
qsirecon-DSIStudio/ |
QSIRecon-DSI Studio | |
qsirecon-DIPYDKI/ |
QSIRecon-DIPY DKI | |
qsirecon-TORTOISE_model-MAPMRI/ |
QSIRecon-TORTOISE MAP-MRI | |
qsirecon-TORTOISE_model-tensor/ |
QSIRecon-TORTOISE Tensor | |
| MR Spectroscopy | osprey/ |
OSPREY-BIDS |
| EEG | made/ |
HBCD-MADE |
| Wearable Sensors | motion/ |
HBCD-Motion |