Page Last Updated: November 29, 2025

Release Notes & History🔗

General Rules Applied to All Data🔗

Exclusions applied to all data
  • Inactive participants/sessions excluded
Field Conversions
  • Empty fields are replaced with 'n/a'
  • Sex is set to 'Other' for participants with only one active Visit 1 (V01) visit
  • 'Candidate_Age' values are replaced with 'n/a' for Visit 1 (V01)

Version: R1.1🔗

Release Date: 2025-10-10

Participants

1,426

Total Visits

2,207

V01: 1,426 | V02: 660 | V03: 121

By Sex (V02/V03)

♀ 328   |   ♂ 338

1.1 Existing Study Data Updates🔗

Domain Table/Data Update/Improvement
Demographics Basic Demographics
sed_basic_demographics		 Reviewed scoring for AOU and ACS EthnoRacial fields. The multiracial options for ACS – Child – Multi Race (child_ethnoracial_acs_by_multi_race) were merged into one due to limited granularity in the child_race field.
Biospecimen & Omics Nails & Urine Toxicology
bio_bm_biosample_*		 Removed 'Specimen ID’ fields from all Biospecimen tables and time from dates in 'Nails Results.'
Pregnancy Exposure, Including Substance Use Pregnancy & Infant Health
pex_bm_health*		 Medications are now categorized into more detailed components based on RxNorm IDs to improve clarity and enable more granular analyses. Additional columns specify: Brand Name, Ingredient, Precise Ingredient, and Multiple Active Ingredients.
Social & Environmental Determinants V01 Demographics
sed_bm_demo		 Added Birth Parent Sexual Orientation variable.
Magnetic Resonance Imaging & Spectroscopy BrainSwipes QC
img_brainswipes*		 Added QC results missing from R1.0 (N=8).

Full Updated Files List ▸

Basic Demographics

  • sed_basic_demographics.json
  • sed_basic_demographics.parquet
  • sed_basic_demographics.tsv

BioSpecimens

  • bio_bm_biosample_nails_results.json
  • bio_bm_biosample_nails_results.parquet
  • bio_bm_biosample_nails_results.tsv
  • bio_bm_biosample_nails_results_shadow.parquet
  • bio_bm_biosample_nails_results_shadow.tsv
  • bio_bm_biosample_urine.json
  • bio_bm_biosample_urine.parquet
  • bio_bm_biosample_urine.tsv
  • bio_bm_biosample_urine_shadow.parquet
  • bio_bm_biosample_urine_shadow.tsv

SPM-2

  • ncl_cg_spm2__inf.json
  • ncl_cg_spm2__inf.parquet
  • ncl_cg_spm2__inf.tsv
  • ncl_cg_spm2__inf_shadow.parquet
  • ncl_cg_spm2__inf_shadow.tsv

TLFB

  • pex_ch_tlfb.json
  • pex_ch_tlfb.parquet
  • pex_ch_tlfb.tsv
  • pex_ch_tlfb_shadow.parquet
  • pex_ch_tlfb_shadow.tsv

PEX Health V2 Preg

  • pex_bm_healthv2_preg.json

1.1 Resolved Known Issues🔗

Demographics ▸
Table/Data Resolved Known Issue
Basic Demographics
sed_basic_demographics
Added income fields (income) originally missing for subset of subjects.
Removed Mother Race (screen_mother_race) variable option #3, a duplicate of option #5 for 'Black African American.'
Removed Gestational/Mother’s Age at Delivery (<gestational|mother>_age_delivery) that occurred after the R1.0 cutoff date of 2025-07-01 (and therefore did not undergo QC).
Removed invalid levels 0 & 1 from Mother Ethnicity (screen_mother_ethnicity). Valid levels remaining: 2 (Hispanic) and 3 (Non-Hispanic).
Added response option ("None of these fully describe me/Other") for Mother Race & Ethnicity (rc_mother_ethnoracial_aou_race_ethnicity).
Visit Information
par_visit_data
Added Substance Use flags (see details) for alcohol, opioid, cannabis, and nicotine.
Behavior, Biology, & Environment ▸
Table/Data Resolved Known Issue
Nails & Urine
bio_bm_biosample_*
Added collection and analysis dates (Collection/Received/Report) to all tables.
Urine
bio_bm_biosample_urine
Corrected 'Urine Specific Gravity' field (bio_spg_u) to floating point values for the appropriate thousandths format (previously set to '1' and data type to 'integer').
Set all negative values for Urinary Toxicology (Cotinine) results (bio_c_cot_u) to ‘0’ (negative values are not biologically plausible).
Corrected negative gestational ages for 2 participants in the Urine dataset.
SPM-2
ncl_cg_spm2__inf
Added verified t-scores (originally excluded due to errors in conversion from raw scores).
Health V2 - Infancy
pex_bm_healthv2_inf
Removed erroneously included descriptive fields 001__00 - 005__00.
APA 1/2
pex_bm_apa
Added summary scores and corresponding T-scores, where appropriate, for Level 2 domains.
EPDS
pex_bm_epds
Removed duplicate data for each item (e.g., epds_001 and epds_001_01).
TLFB
pex_ch_tlfb
Corrected logic for TLFB substance use flags. Previously, only the alcohol use flag applied the intended criteria (use during or after pregnancy across V01–V02).
Removed age variable fields (gestational_age, adjusted_age, and candidate_age) due to incorrect values.
Brain Activity & Biosensors ▸
Table/Data Resolved Known Issue
HBCD-MADE Derivatives
Removed erroneous resting-state summary files (*_task-RS_powerSummaryStats.csv) due to a pipeline bug. Users can generate these summary statistics with HBCD EEG Utilities.

Version: R1.0🔗

Release Date: 2025-06-26

Participants

1,426

Total Visits

2,207

V01: 1,426 | V02: 660 | V03: 121

By Sex (V02/V03)

♀ 328   |   ♂ 338

Participant & Visit Exclusions🔗

Excluded Participants
  • Participants with no brain rating or brain rating noted as "atypical"
  • Postnatal Recruitment participants
  • Multiple Birth participants
Excluded Visit Data
  • Visits with 'LaunchPad Complete' Status set to 'Complete' after 2024-07-01.

Instrument & Field Exclusions🔗

Click to Expand ▸

Instrument Exclusions

Instrument(s) Table Name(s)
Biosensor Receipt Formsens_ch_rcpt
EEG Acquisition Checklistseeg_ch_chkl / eeg_ch_chkl_<1|2>
ERICA formsmh_cg_erica_<3_7m|7_9m> / mh_cg_erica_fcm_adm_<3_7m|7_9m>
GABI Setup/Receiptnt_pa_gabi_setup / nt_pa_gabi_rcpt
MRI Checklists & Pre/Post Scan Prepmri_ra_chkl_data / mri_ra_chkl_scan / mri_ra_prep
NIH Baby ToolBoxncl_ch_nbtb
Participant / RA Feedbackadm_cg_fb / adm_ra_fb
Transitions in Care Questionnairesed_cg_tic
Urgent Events & Participant Alertsadm_fd_urgent / admin_alert
Visit Start / Visit Level Datavisit_start / adm_fd_visitdata

Instrument Field Exclusions

Table Field(s) Field Name(s)/Details
Date of Administrationdate_taken
Examinerexaminer
REDCap Complete statuscomplete
Timestampstimestamp / timestamp_start / timestamp_stop / timestamp_redcap_locked
Visit Datavisit_stage removed from the visit_data category
Breast Feeding History Fieldsph_cg_phx_i_bfh – All fields except 001 excluded
Height/Weight/Head Circumference BMIph_ch_anthro – BMI-related fields removed