Page Last Updated: October 10, 2025
Study Instruments
The current release includes data from Visits 1, 2, and 3 (V01, V02, and V03) for the majority of measures. In this section we provide a brief overview of each study instrument provided in the data release, including, where applicable, details of implementation and data collection, scoring procedures, quality control procedures, data and responsible use warnings, and references. Full study protocols are available on the HBCD Study site . See Pending Updates for details on what to expect in future releases.
HBCD Study data includes both tabulated and file-based data - see Data Structure Overview for details. In summary:
Tabulated data contain data across all participants in a standardized tabulated format for HBCD (includes Behavior, Biospecimens/Toxicology, Demographics, data derived from MRI and other file-based data, etc. ).
File-based data include raw and processed derivative data organized under subject/session-level folders and are in varied modality-specific formats (includes MRI/MRS, EEG, and Wearable Sensors data ).
Expand the sections below to see a list of measures associated with each domain included in the latest release data.
Instruments by Domain
Click domain headers (e.g., Biospecimen & Omics ) to expand and view domain measures.
Click instrument names (e.g., Nails ) to access detailed instrument documentation.
Expand All Sections ↕️
Demographics
Instrument
Construct
Tabulated Data Table Name
Tabulated Data
Basic Demographics
Demographics data derived from multiple sources
sed_basic_demographics
Tabulated Data
Visit Information
Participant visit information
par_visit_data
Behavior, Biology, & Environment
Behavior & Caregiver-Child Interaction
▸
Instrument
Version
Construct
Tabulated Data Table Name
Tabulated Data
ecPROMIS-Ch/CG Interaction
<1 year
Child/Caregiver Relationship
mh_cg_pms__cc__inf
Tabulated Data
BQ (VSF)+BI
IBQ-R (VSF)+BI (Infant )
Surgency/Extraversion, Negative Affectivity, Effortful Control, Behavioral Inhibition
mh_cg_ibqr
Tabulated Data
MAPS-TL
Infancy (< 1 year)
Irritability
mh_cg_mapdb__inf
Instrument
Version
Construct
Tabulated Data Table Name
Tabulated Data
Nails
Maternal
Drug, Environmental Exposure
bio_bm_biosample_nails_resultsbio_bm_biosample_nails_type
Tabulated Data
Urine
Maternal
Drug Panel, Toxins
bio_bm_biosample_urine
Neurocognition & Language
▸
Instrument
Version
Construct
Tabulated Data Table Name
Tabulated Data
MLDS
Multilingual Exposure
ncl_ch_mlds
Tabulated Data
SPM-2
Infant
Sensory Processing/Integration
ncl_cg_spm2__inf
Pregnancy & Exposure, Including Substance Use
▸
Instrument
Ver
Construct
Tabulated Data Table Name
Tabulated Data
Health V1-Health History
Pre-pregnancy and pregnancy health
pex_bm_health_preg__healthhx
Tabulated Data
Health V1-Exp & Vaccines
Vaccines in pregnancy
pex_bm_health_preg__exp__vacc
Tabulated Data
Health V1-Chronic Conditions
Chronic conditions/STIs in pregnancy
pex_bm_health_preg__chroncond
Tabulated Data
Health V1-Illness
Illness in pregnancy
pex_bm_health_preg__illness
Tabulated Data
Health V1-ER Admissions
ER visit or hospitalization in pregnancy
pex_bm_health_preg__erhosp
Tabulated Data
Health V1-Medications
Medications in pregnancy
pex_bm_health_preg__meds
Tabulated Data
Health V2-Pregnancy
Health updates up to delivery
pex_bm_healthv2_preg
Tabulated Data
Health V2-Infancy
Delivery and birth outcomes
pex_bm_healthv2_inf
Tabulated Data
FAM MH
Personal and Family Mental Health
pex_bm_psych
Tabulated Data
APA 1/2
Mental Health
pex_bm_apa
Tabulated Data
DSM5 Acute Stress or PTSD
PTSD/Acute Stress Symptom Severity
pex_bm_str__ptsd
Tabulated Data
EPDS
Postnatal Depression
pex_bm_epds
Tabulated Data
ASSIST
V1
SU Before and During Pregnancy
pex_bm_assistv1
V2
SU, Pregnancy End & Postnatal
pex_bm_assistv2
V3
SU After Pregnancy (3 mo anchors)
pex_bm_assistv3
Tabulated Data
TLFB
SU Before and During Pregnancy
pex_ch_tlfb
Social & Environmental Determinants
▸
Instrument
Version
Construct
Tabulated Data Table Name
Tabulated Data
BFY
Benefits/Services, Economic Stress
sed_bm_bfy
Tabulated Data
HBCD Demographics
V1
Demographics (Adult Visit 1)
sed_bm_demo
Tabulated Data
eHITS
Intimate Partner Violence
sed_bm_ehits
Tabulated Data
Neighborhood Safety
Neighborhood Safety
sed_bm_nbhsaf
Tabulated Data
PACES
<18
Protective Factors
sed_bm_paces
Tabulated Data
PROMIS
Perceived Stress/Social Support
sed_bm_strsup
Tabulated Data
Unfair Treatment
Experiences of Unfair Treatment
sed_bm_phx__discr
Brain Activity & Biosensors
File-Based Data Raw BIDS
File-Based Data Derivatives [Source Pipeline ]
Tabulated Data Tables Derived from Pipeline Derivatives
sMRI Structural MRI
anat/
bibsnet/ [BIBSNet ]
img_bibsnet_space-<T1w|T2w> _desc-aseg_volumes
mriqc/ [MRIQC ]
img_mriqc_<T1w|T2w>
nibabies/ [Infant-fMRIPrep ]
None
xcp_d/ [XCP-D ]
img_xcpd_space-fsLR_seg-<PARC> _stat-mean_desc-curv_morph
img_xcpd_space-fsLR_seg-<PARC> _stat-mean_desc-sulc_morph
img_xcpd_space-fsLR_seg-<PARC> _stat-mean_desc-thickness_morph
NA - BrainSwipes QC results
img_brainswipes_xcpd-T2w
fMRI Functional MRI
func/
mriqc/ [MRIQC ]
img_mriqc_bold
nibabies/ [Infant-fMRIPrep ]
None
xcp_d/ [XCP-D ]
img_xcpd_space-fsLR_seg-<PARC> _stat-alff_bold
img_xcpd_space-fsLR_seg-<PARC> _stat-coverage_bold
img_xcpd_space-fsLR_seg-<PARC> _stat-reho_bold
NA - BrainSwipes QC results
img_brainswipes_xcpd-bold
qMRI Quantitative MRI anat/
qmri_postproc/ [qMRI Postproc ]
None
dMRI Diffusion MRI
dwi/
qsiprep/ [QSIPrep ]
img_qsiprep_space-ACPC_desc-image_qc
qsirecon/ [QSIRecon ]
None
qsirecon-DSIStudio/
None
qsirecon-DIPYDKI/
None
qsirecon-TORTOISE_model-MAPMRI/
None
qsirecon-TORTOISE_model-tensor/
None
MRS MR Spectroscopy mrs/
osprey/ [OSPREY-BIDS ]
img_osprey_<Q> _AlphaCorrWaterScaledGroupNormed_Voxel_1_Basis_1
img_osprey_<Q> _AlphaCorrWaterScaled_Voxel_1_Basis_1
img_osprey_<Q> _CSFWaterScaled_Voxel_1_Basis_1
img_osprey_<Q> _TissCorrWaterScaled_Voxel_1_Basis_1
img_osprey_<Q> _rawWaterScaled_Voxel_1_Basis_1
img_osprey_<Q> _amplMets_Voxel_1_Basis_1
img_osprey_<Q> _tCr_Voxel_1_Basis_1
img_osprey_HERCULES_qm_processed_spectra
img_osprey_unedited_qm_processed_spectra
Label Values Legend
<PARC> (parcellations): 4S-<156|256|...|1056>Parcels, Glasser, Gordon, MIDB, MyersLabonte, HCP, Tian (HCP & Tian functional only)
<Q> (quantification method): HERCULES_diff1, HERCULES_diff2, HERCULES_sum, unedited_A
Novel Technologies & Wearable Sensors
▸
Sensor
Data Type
Construct
Tabulated Data Table Name / File-Based Data Folder
Infant Leg Motion
Tabulated Data
Questionnaire 1/2/3
Motor Development, Regulation (Sleep/Wake)
nt_ch_sens__qtn_<1|2|3>
File-Based Data
Raw BIDS
rawdata/sub-{ID}/ses-{V0X}/motion/
File-Based Data
Derivatives
derivatives/hbcd-motion/